The clinical scenarios below describe four different types of immunological exposure in patients:

• Scenario I: A patient receives an intravenous infusion of convalescent serum containing neutralizing IgG antibodies harvested from a recovered donor.
• Scenario II: An individual is infected via respiratory droplets with the live, active pathogen, resulting in a mild fever and subsequent recovery.
• Scenario III: A volunteer is injected with a vaccine containing a purified, recombinant surface glycoprotein of the pathogen.
• Scenario IV: An infant receives secretory IgA antibodies directed against the pathogen via colostrum and breast milk.

Which of these scenarios will result in the clonal selection, clonal expansion, and differentiation of the recipient's own lymphocytes, thereby providing long-term active immunity?