In a human bone marrow stem cell undergoing active cell cycles to replenish the blood supply, several biochemical and physical processes must occur in a highly coordinated sequence.

Consider the following processes:

1. Synthesis of histone proteins and replication of genomic DNA.
2. Transcription and translation of tubulin genes to produce spindle fibres.
3. Separation of homologous chromosome pairs to opposite poles of the cell.

Which of these processes occur during the cell cycle of a cell dividing by mitosis?