Hematopoietic stem cells in the adult bone marrow undergo cell division and differentiation to produce specialized blood cells, such as erythrocytes and neutrophils. Which of the following statements about these cells is not correct?
Hematopoietic stem cells are pluripotent stem cells, allowing them to differentiate into any specialized cell type of the human body, including muscle and nerve cells, depending on chemical signals.
Mature erythrocytes lack a nucleus, mitochondria, and rough endoplasmic reticulum, maximizing space for haemoglobin but meaning they must rely entirely on anaerobic respiration.
Mature neutrophils possess a multi-lobed nucleus, which increases their flexibility to squeeze through narrow capillary pores, and a large number of lysosomes to digest engulfed pathogens.
The process of differentiation from stem cells to mature blood cells involves the selective activation and silencing of specific genes, which determines the final proteome of each cell type.
