Name the endocrine gland that secretes antidiuretic hormone (ADH) into the blood in response to stimulation from osmoreceptors.
Cranial diabetes insipidus is a physiological disorder characterised by a severe deficiency in the secretion of ADH. Suggest two clinical signs or physiological changes in the urine or blood of a patient with this condition.
Explain the cellular mechanism by which ADH increases the permeability of the collecting duct cells to water once it has bound to its specific receptors.