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Cell recognition and the immune system

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Question 9

Melibiose is a disaccharide found in some plant-derived pathogens.

Melibiose is formed from one molecule of glucose and one molecule of galactose. Both glucose and galactose are hexose monosaccharides with the chemical formula C6H12O6\text{C}_6\text{H}_{12}\text{O}_6C6​H12​O6​.

a.

Give the chemical formula for the disaccharide, melibiose, and describe how it is formed from glucose and galactose.

[2]
b.

In some agricultural workers, inhalation of pathogen spores triggers an immune response where antibodies are produced against surface glycoproteins containing melibiose. Draw a labelled diagram of an antibody and identify the specific site where melibiose would bind.

[3]
c.

Suggest how a single antibody can show cross-reactivity, binding specifically to both the plant-derived melibiose and a structurally distinct bacterial membrane protein.

[2]

Cell recognition and the immune system Questions

  1. A Level
  2. /Biology
  3. /Cell recognition and the immune system