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Cell recognition and the immune system

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Question 4

In the following passage, each numbered space can be filled with a biological term.

Pathogens possess specific molecules on their outer surface known as (1) ___________ which trigger an immune response. In response to these, B-lymphocytes differentiate into (2) ___________ cells that secrete (3) ___________, which are Y-shaped (4) ___________ constructed of four polypeptide chains. This cellular or humoral response is an example of (5) ___________ immunity. Vaccination campaigns aim to achieve (6) ___________ immunity, protecting unvaccinated individuals by significantly reducing transmission within the population.

a.

Write the correct biological term beside each number from 1 to 6 that matches the space in the passage.

[6]
b.

Influenza requires a new vaccine formulation to be developed and administered every year. Suggest one reason why.

[1]
c.

Table 1 shows the action of two antimicrobial agents.

Antimicrobial agentAction of antimicrobial
RifampicinInhibits bacterial RNA polymerase, preventing transcription of DNA.
VancomycinInhibits the synthesis of peptidoglycan in cell walls.

Using the information in Table 1, explain why each antimicrobial agent is not effective against the influenza virus.

  • Rifampicin
  • Vancomycin
[2]

Cell recognition and the immune system Questions

  1. A Level
  2. /Biology
  3. /Cell recognition and the immune system