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Cell recognition and the immune system

Cell recognition and the immune system

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Question 14

In the following passage, each numbered space can be filled with a biological term.

In the cell-mediated immune response, foreign (1) ___________ are displayed on the surface of host cells, turning them into (2) ___________-presenting cells. Receptors on specific T-lymphocytes bind to these, triggering rapid division by mitosis, a process known as clonal (3) ___________. These T-cells differentiate into helper T-cells, which release (4) ___________ to stimulate B-cells, or cytotoxic T-cells, which destroy infected host cells. The production of a person's own antibodies and memory cells results in (5) ___________ immunity. Conversely, the direct transfer of pre-formed antibodies, such as across the placenta, provides immediate but temporary (6) ___________ immunity.

a.

Write the correct biological term beside each number from 1 to 6 that matches the space in the passage.

[6]
b.

Developing an effective vaccine against the Human Immunodeficiency Virus (HIV) has proven extremely challenging. Suggest one reason why.

[1]
c.

Table 1 shows the action of two antimicrobial agents.

Table 1

Antimicrobial agentAction of antimicrobial
TetracyclineBinds to bacterial 70S ribosomes, preventing translation of mRNA.
PenicillinInhibits the transpeptidase enzyme, preventing the cross-linking of peptidoglycan in bacterial cell walls.

Using the information in Table 1, explain why each antimicrobial agent is not effective against the Human Immunodeficiency Virus (HIV).

  • Tetracycline
  • Penicillin
[2]
Markscheme

Cell recognition and the immune system Questions

  1. A Level
  2. /Biology
  3. /Cell recognition and the immune system

14 exam-style questions on AQA A Level Biology Cell recognition and the immune system, covering Cell recognition and the immune system. Each one has a worked solution and a mark scheme showing where the marks go.

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